Value of colony forming unit-granulocyte macrophage assay in predicting relapse in acute myeloid leukaemia.
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چکیده
منابع مشابه
Value of colony forming unit-granulocyte macrophage assay in predicting relapse in acute myeloid leukaemia.
AIM To evaluate the validity of the colony forming unit-granulocyte macrophage (CFU-GM) assay for predicting relapse in patients with acute myeloid leukaemia (AML). METHODS The study population comprised 32 patients with AML in remission, followed for a median of 18 months. A mean of four studies was carried out per patient. Three patterns of in vitro growth based on the number of CFU-GM in n...
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متن کاملInterleukin-10 inhibits spontaneous colony-forming unit-granulocyte-macrophage growth from human peripheral blood mononuclear cells by suppression of endogenous granulocyte-macrophage colony-stimulating factor release.
Spontaneous growth of myeloid colonies (colony-forming unit-granulocyte-macrophage [CFU-GM]) can be observed in methylcellulose cultures containing peripheral blood mononuclear cells (PB-MNCs) and is supposedly caused by the release of colony-stimulating factors (CSF) by accessory cells. Because of its cytokine synthesis-inhibiting effects on T lymphocytes and monocytes, interleukin-10 (IL-10) ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1996
ISSN: 0021-9746
DOI: 10.1136/jcp.49.6.450